HGH Mechanisms of Action & Physiology

• Frost RA, et al. "Regulation of IGF-I mRNA and signal transducers and activators of transcription-3 and -5 (Stat-3 and -5) by GH in C2C12 myoblasts."
• Møller N, Jørgensen JO. "Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects."
• Giustina A, Veldhuis JD. "Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human."
• Laron Z. "Insulin-like growth factor 1 (IGF-1): a growth hormone."
• Gosteli-Peter MA, et al. "Expression and regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein messenger ribonucleic acid levels in tissues of hypophysectomized rats."
• Epelbaum, Jacques. "Neuroendocrine Regulation of Growth Hormone Secretion."
• Vélez EJ, Unniappan S. "A Comparative Update on the Neuroendocrine Regulation of Growth Hormone in Vertebrates."

Pharmacokinetics & Administration

• Ho KY, et al. "The pharmacokinetics, safety and endocrine effects of authentic biosynthetic human growth hormone in normal subjects."
• Hansen TK, et al. "Body composition and circulating levels of insulin, insulin-like growth factor-binding protein-1 and growth hormone binding protein affect the pharmacokinetics of GH in adults independently of age."
• Tanaka T, et al. "Pharmacokinetics and metabolic effects of high-dose growth hormone administration in healthy adult men."
• Bick T, et al. "Roles of pulsatility and continuity of growth hormone administration in the regulation of hepatic GH-receptors."
• RUSSO L, MOORE WV. "A Comparison of Subcutaneous and Intramuscular Administration of Human Growth Hormone in the Therapy of Growth Hormone Deficiency."
• Takano K, et al. "A comparison of subcutaneous and intramuscular administration of human growth hormone and increased growth rate by daily injection of hGH in GH deficient children."
• Laursen T, et al. "Metabolic effects of growth hormone administered subcutaneously once or twice daily to growth hormone deficient adults."
• Höybye C, Rudling M. "Long-term GH treatment of GH-deficient adults: comparison between one and two daily injections."
• Jørgensen JOL, et al. "Pharmacological Aspects of Growth Hormone Replacement Therapy: Route, Frequency and Timing of Administration."

Body Composition & Performance Effects

• Meinhardt U, et al. "The effects of growth hormone on body composition and physical performance in recreational athletes: a randomized trial."